Scutellaria barbata D.Don is a popular Chinese medicinal plant documented to treat cancer patients in traditional Chinese medicine (TCM). 2016; 182:170-80 (ISSN: 1872-7573) Tao G; Balunas MJ. It is a perennial herb, which grows to a height of 1-4 feet. Plant prefers part shade to… Current therapeutic role and medicinal potential of Scutellaria barbata in Traditional Chinese Medicine and Western research. It can limit the growth of cancer cells. valuable medicinal species: Scutellaria barbata Tie-shan Wang, Sui-qiong Wang and Da-li Xiao* Department of Pharmacy, Guangdong Women and Children Hospital, Guangzhou 510010, China. Description. Jia-Wei-Xiao-Yao-San (19.6%) and Hedyotis diffusa (41.9%) were the most commonly prescribed herbal formula (HF) and single herb (SH), respectively. ---Part Used---Herb. It is a perennial herb generally reaching up to 35 centimeters tall, sometimes taller. S. barbata is a common herb that you can find in Korea, southern China and Vietnam. It can grow in semi-shade (light woodland) or no shade. Traditional usage (TCM): clears heat, infection, tumors, hepatitis. It has four-angled stems with multiple opposite leaves. S. barbata has been found to exhibit efficacy both in vitro and in vivo on a variety of cancer types. Scutellaria barbata, also known as Ban Zhi Lian or barbat skullcap, is a perennial herb of the Lamiaceae (mint) family that grows on moist flatlands in southeastern China (Dharmananda, 2004, Li and Hedge, 2014).Typically harvested in late summer when the plant is in full bloom, the aerial parts of these flowering herbs are dried to use as medicine (Dharmananda, 2004). The species is hermaphrodite (has both male and female organs) and is pollinated by Insects. A botanical new investigational drug for breast cancer BZL101 (FDA IDN# 59521) was previously developed in the United States from the aqueous extract of the aerial parts from S. barbata. Scutellaria barbata D.Don is a popular Chinese medicinal plant documented to treat cancer patients in traditional Chinese medicine (TCM). The content of chemical marker scutellarin in SBW was quantified using UPLC. The American species, Virginian Scullcap, flowering in July, with inconspicuous blue flowers in one-sided racemes, is one of the finest nervines ever discovered. However, the effect of this couplet on tumor cell migration has not been elucidated. D.Don. The lightly toothed leaves are somewhat lance-shaped or triangular and up to about 3 centimeters long. J Ethnopharmacol. Although there are some uses of Scutellaria in clinical practice, the existing research on this genus is still limited. This study investigated the effects of SB on prostate cancer prevention. S. barbata has been found to exhibit efficacy both in vitro and in vivo on a variety of cancer types. Similarly encouraging results have been shown in patients with metastatic breast cancer from Phase Ia and Ib clinical trials. Popularly this plant is known in America as Mad-dog Scullcap or Madweed, having the reputation of being a certain cure for hydrophobia. Scutellaria baicalensis is a PERENNIAL growing to 0.3 m (1ft) by 0.3 m (1ft in). Description of the plant: Scutellaria barbata is a ANNUAL growing to 0.4 m (1ft 6in). Native to southeastern China. This study aims to … Overview Information Skullcap is a plant. Hi Melinda, Thank you for mentioning the Scutellaria barbata. The above ground parts are used to make medicine. Scutellaria barbata: A Chinese herb that belongs to a group of herbs named Scutellaria (scullcap or skullcap). This study investigated the effects of SB on prostate cancer prevention. Scutellaria barbata has been used for cancer treatments. Skullcap is a powerful medicinal herb and it is used in alternative medicine as an anti-inflammatory, abortifacient, antispasmodic, slightly astringent, emmenagogue, febrifuge, nervine, sedative, and a strong tonic. Male TRansgenic Adenocarcinoma Mouse Prostate (TRAMP) mice at 9 weeks were randomly divided into four groups and given daily oral feedings of 8, 16, or 32 mg SB or sterilized water. This finding illustrates the importance of performing additional clinical trials of Scutellaria barbata and the duplex medicinal of Scutellaria barbata plus Hedyotis diffusa. Scutellaria baicalensis is also called Baical or Chinese Scutellaria, or Scullcap. It is hardy to zone (UK) 5. Scutellaria baicalensis, also known as Chinese skullcap, is a perennial flowering plant highly prized for its reputed medicinal properties. ETHNOPHARMACOLOGICAL RELEVANCE: Scutellaria barbata is a common herb in Traditional Chinese Medicine (TCM) most often used to treat cancer. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils. Scutellaria ocmulgee. Accepted 2 March, 2012 Scutellaria barbata belonging to the genus Scutellaria L. (Labiatae) is a perennial herb which is natively distributed throughout Korea and Southern China. The plant Scutellaria barbata (SB) is commonly used as herbal medicines for treating cancer. This herb really grows well for us and I think it is somewhat stouter and tougher than most of the other species of skullcap. Scutellaria baicalensis georgi from the Lamiaceae family is said to be one of the potent medicinal herbs and is thus used to treat a number of health disorders for over two thousand years. ETHNOPHARMACOLOGICAL RELEVANCE: Scutellaria barbata is a common herb in Traditional Chinese Medicine (TCM) most often used to treat cancer. Depurative, diuretic, febrifuge. FOLKLORE AND USES IN ALTERNATIVE MEDICINE . Madweed. The present pre‐clinical study aimed to validate the Chinese Pharmacopoeia (CP) recommended dosages of SB water extract (SBW) in treating colon tumors. Traditional use (TCM): small doses usually combined with other herbs to treat breast cancer. Scutellaria barbata, the barbed skullcap, is a species of flowering plant in the mint family, Lamiaceae. The herb is also considered antiinflammatory and is used to treat infections. It is native to Asia. Here, we report chromosome-level genome assemblies of 4.4. Clinical Overview Use. TCM is commonly used to treat breast cancer patients ; however, there is little information available on the core CHM treatments prescribed by TCM practitioners. It is in flower from May to July, and the seeds ripen from June to August. Scullcap traditionally has been used as a sedative for nervousness and anxiety, although data are limited to support this use. Scutellaria barbata (SB) has been used in Chinese medicine to treat various cancers. Flowers large and blue/purple. Medicinal Action and Uses---Synonyms---Mad-dog Scullcap. Both produce specific flavonoid compounds, including baicalein, scutellarein, norwogonin, wogonin, as well as their glycosides, that exhibit antioxidant and antitumor activities. Family: Mint (Lamiaceae) Hardy to Zones 7 to 10 (Barbat Skullcap, Ban-zhi-lian) Herbaceous perennial to 18 inches. The species is hermaphrodite (has both male and female organs). J … The low-growing plant bears flowers that vary from blue to purple. Baikal Skullcap grows at 100-200 meters above sea level and is part of the rich biodiversity of flora and fauna native to the Lake Baikal region, in Siberia. Hedyotis diffusa plus Scutellaria barbata is a couplet of medicinal that has been commonly used to treat inflammation-related diseases and various types of tumors. Benefit for mood disturbance has also been demonstrated. Limit doses of American skullcap to no more than … Current Therapeutic Role and Medicinal Potential of Scutellaria barbata in Traditional Chinese Medicine and Western Research Posted: February 26th, 2016 By: Zeyiad Elias Current Western research related to S. barbata is focused on cancer treatment, which corresponds to the most common use of S. barbata by TCM practitioners. For example, there is often confusion between Scutellaria baicalensis, Scutellaria lateriflora and Scutellaria barbata, with the latter two plants being given the name Baikal Skullcap by many gardeners in North America. In addition, studies have shown that S. barbata is one of medicinal plants used in cancer treatment. ETHNOPHARMACOLOGICAL RELEVANCE: Scutellaria barbata is a common herb in Traditional Chinese Medicine (TCM) most often used to treat cancer. The root has been used in traditional Chinese medicine to treat Suitable for: light (sandy) and medium (loamy) soils and prefers well-drained soil. Dosing. A botanical new investigational drug for breast cancer BZL101 (FDA IDN# 59521) was previously developed in the United States from the aqueous extract of the aerial parts from S. barbata. The aim of this study was to examine the anti-cancer effects and precise regulatory mechanisms of SB in CL1-5 lung cancer cells. Latin name: Scutellaria barbata Family: Labiatae Medicinal use of Barbed Skullcap: Used as a detoxicant, mainly in the treatment of certain types of cancer, liver diseases, pharyngitis and poisonous bites. Suitable pH: acid, neutral and basic (alkaline) soils. Benefits and Drawbacks of This Study. Scutellaria barbata has a long history of medical use in Traditional Chinese Medicine for removing heat and toxic material, promoting blood circulation and removing blood stasis, and inducing diuresis to reduce edema. Similarly encouraging results have been shown in patients with metastatic breast cancer from Phase Ia and Ib clinical trials. Scutellaria barbata (SB) has been used in Chinese medicine to treat various cancers. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. Both the root and the above-ground part of Scutellaria barbata have been used to make herbal medicines. Along with other herbs, it is used to treat bacterial infections, hepatitis, and tumors. It is related to mint. Scutellaria barbata D. Don (SB), which is derived from the dried whole plant of Labiatae, is a well-known anti-inflammatory and anti-cancer herb. Association rule mining and network analysis identified Hedyotis diffusa plus Scutellaria barbata as the most common duplex medicinal (10.9%) used for the core treatment of breast cancer. The juice of the plant is applied to wounds. Chinese skullcap (Scutellaria baicalensis) is an herb commonly used in traditional Chinese medicine. It is in flower in August, and the seeds ripen in September. Scutellaria barbata D.Don (S. barbata), commonly known as Ban Zhi Lian in China and belong to the family Lamiaceae , is a pop- ular medicinal plant ( Figure 1 ) with a long history of use in Scutellaria barbata has a long history of medical use in Traditional Chinese Medicine for removing heat and toxic material, promoting blood circulation and removing blood stasis, and inducing diuresis to reduce edema. Scutellaria barbata D.Don (S. barbata), commonly known as Ban Zhi Lian in China and belong to the family Lamiaceae, is a popular medicinal plant with a long history of use in traditional Chinese medicine (TCM).The plant name was first documented in “Wai Ke Zheng Zong” by Shigong Chen in 1617 ad. Scientific Name(s): Scutellaria lateriflora L. Common Name(s): Helmetflower, Hoodwort, Mad-dog weed, Scullcap, Skullcap. 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